Steve Jobs Final Legacy advances Personalized Medicine

I am so excited about how information technology is starting to influence biomedical research and patient treatment. The so called “Translational Medicine” or “bench to bedside” approach is is a key part of the P4 Medicine (Prediction, Prevention, Personalization and Participation) Model that we will all be using in a few years. P4 Medicine is already an established protocol for many of small and medium size health insurance plans.
One of the leading companies is cancer diagnostics darling Foundation Medicine whose stock closed at $35.35 on its first day of trading, which  Dow Jones noted was a whopping 96% higher than the debut price of $18 per share. Friday’s (October 4, 2013) close was slightly lower at $33.43.
Steve Jobs pictured here with Bill Gates (a key investor in Foundation Medicine) believed the future is in personal medicine was taking strides. He famously said, “I’m either going to be one of the first to be able to outrun a cancer like this, or I’m going to be one of the last to die from it.”

Steve Jobs pictured here with Bill Gates (a key investor in Foundation Medicine) believed the future is in personal medicine was taking strides. He famously said, “I’m either going to be one of the first to be able to outrun a cancer like this, or I’m going to be one of the last to die from it.”

 
Starting in spring of 2014, for about $5,000, an oncologist will be able to ship a sliver of your tumor in a bar-coded package to Foundation’s lab, where the DNA will be extracted, sequence scores of cancer genes, and prepare a report to steer doctors and patients toward drugs and current clinical trials. The company’s test, called Foundation One, essentially offers the public, DNA screening test that sequences the 236 genes involved in cancer, detailing the dangerous mutations that are causing them to grow. Once complete your physician will be given assistance to potential treatment including any current clinical trails addressing the molecular subtype structure of your tumor.This comprehensive cancer diagnostic test represents a critical step towards individualized cancer care by helping physicians recommend treatment options for each patient based on the molecular subtype of their cancer. Knowing the molecular subtype along with your personal vitals (height, weight, metabolism and environment) will reduce the time to connect you to the best alternatives for treatment. With cancer time really does matter.
Savvy tech Investors like Google (9%) and Bill Gates (4%) see DNA structures as digital molecules that will become increasingly cheaper and faster to decode the genetic data and translate into an action. These entrepreneurial tech executives understand the business potential this offers when connected to genetics labs and how one day it will be delivered through a mobile device. Already Google Ventures has helped the Foundation technicians build software called the Interactive Cancer Explorer (see this promotional video) so doctors can access DNA reports on patients.
This is a small step that will lead to huge changes in the means, cost and effectiveness of health outcomes in the future.
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